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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Plantar Fasciitis Medical Devices That Relieve Pain

Plantar Fasciitis Medical Devices That Relieve Pain

SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

The Physics of Shock Wave Lithotripsy

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Shock wave treatment for in vitro engineering applications

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Can cellulite be treated with low-energy extracorporeal shock wave therapy?

Adhesive Capsulitis Management with Advanced Shockwave Therapy

SoftWave: Empowering Adhesive Capsulitis Management with Advanced Shockwave Therapy

Shockwave Therapy for Calcific Tendonitis

Extracorporeal shockwave therapy induces alveolar bone regeneration

Macrophage migration induces angiogenesis

Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

SoftWave Therapy® Represents a Valuable Addition in the Treatment of Hard-to-Heal Wounds

ESWT Therapy for Treatment of Keloid Scars

Case Study 1 shows an 80-year old female patient who developed a large infected decubitus ulcer from a lengthy stay in a hospital bed following a knee operation.

Softwave application on hand

Healing at the Edge of the World: How Dr. Paul Kratka Brings SoftWave to the South Pacific

TISSUE REGENERATION TECHNOLOGIES, LLC Establishment Registration & Device Listing

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

Dermapace Machines- Cost, Efficacy, & Alternatives

Dermapace Machines: Cost, Efficacy, & Alternatives

Biological Principles – Mechanotransduction

Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells

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Is it possible to change the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Variable Sound-Fields of Electro-Hydraulic Extracorporeal Shockwave Applicators

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

​Shock waves for arthritis A new form of therapy offers pain relief using sound waves in pets

Exploring Regenerative Treatment for Knees After Failed Conservative Care

Regenerative Treatment for Knees That Fail Conservative Care

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

Best Noninvasive Options for Regenerative Back Treatment Without Injections

Best Options for Regenerative Back Treatment Without Injections

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Extracorporeal shock wave therapy effectively prevented diabetic neuropathy

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A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

Extracorporeal shockwave: mechanisms of action and physiological aspects…

Acoustic Wave Therapy vs Shockwave Therapy

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

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DIGEST Guidelines for Extracorporeal Shock Wave Therapy

Minimally invasive treatment of Peyronie’s disease: evidence-based progress

Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis​

Mesenchymal stem cells: Myths and reality

Linear Shockwave Therapy in Clinical Practice- Evidence and Mechanisms

Linear Shockwave Therapy Mechanisms and Efficacy Explained

Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

Shock wave treatment induces angiogenesis and mobilizes endogenous cd31/cd34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis

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Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

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Effects of Extracorporeal Shock Wave Therapy on Spasticity in Patients after Brain Injury: A Meta-analysis

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First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

SoftWave Therapy for Knees

SoftWave Therapy vs. Stem Wave & Acoustic Wave Devices for Knee Pain

The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

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Evidence supporting extracorporeal shockwave therapy for acute and chronic soft tissue wounds

AUVA letter‒ Successful treatment of delayed and non-union fractures

ESWT in skin & aesthetic indications

Extracorporeal Shockwave Treatment Impedes Tooth Movement in Rats

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Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

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Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

SoftWave Celebrates Pro Success of Golfer Jake Peacock and Baseball Player Reid Worley, Highlighting Injury Prevention Breakthroughs

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Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

“In vitro” and multicolor phenotypic characterization of cell subpopulations identified in fresh human adipose tissue stromal vascular fraction and in the derived mesenchymal stem cells

Renova Shockwave Therapy- What Is It & Does It Work for Patients?

Renova Shockwave Therapy: What Is It & Does It Work for Patients?

Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

EPAT Therapy Side Effects & Contraindications

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Molecular changes in diabetics foot ulcers

Athletic therapy (Mts-Science)

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

What Is Pneumatic Shockwave Therapy?

What Is Pneumatic Shockwave Therapy?

Shock Waves Reach Dental Implantology (Spanish)

Best Medical Devices for Treating ACL Injuries 

Best Medical Devices for Treating ACL Injuries 

Chattanooga Intelect Shockwave Machine- Evidence, Mechanisms, and Clinical Context

Chattanooga Intelect Shockwave Machine: Efficacy & Alternatives

opioids united states

FDA Tightens Opioid Warning Labels: Here’s the Non-Invasive Alternative Changing Pain Care

Peripheral Nerve Regeneration

Peripheral Nerve Regeneration

Shockwave Therapy Helping Patients With Peripheral Artery Disease

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Relief for Back Pain with Innovative Shockwave Therapy

SoftWave ESWT: Redefining Relief for Back Pain with Innovative Shockwave Therapy

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Regenerative Skin Treatment for Burns, Scars, and Wounds

Regenerative Skin Treatment for Burns, Scars, and Wounds

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Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

EPAT Therapy for Plantar Fasciitis vs Alternatives

​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

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Case Series of Weekly Low Intensity Shock Wave Therapy for Erectile Dysfunction

​Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin Angiotensin System

Baker’s Cysts

Best Medical Devices for Treating Baker’s Cysts

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

The Use of Shock Waves in Peripheral Nerve Regeneration:New Perspectives?

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

Exploring Alternatives to Pain Treatment: Your Path to Natural Relief

Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain syndrome of the trapezius.

The effect of shock waves on in vitro cartilage development in silk scaffolds

ESWT for Acute and Chronic Soft Tissue Wounds

What Is HydroWave Therapy? Mechanism, Applications, and Clinical Context

What Is HydroWave Therapy? How It Works, Clinical Uses, and Evidence

Shock wave treatment after hindlimb ischaemia results in increased perfusion and M2 macrophage presence

​Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease.

Radial or Focused Shockwave Therapy? When to Use Each in Clinical Practice

Radial or Focused Shockwave Therapy? When to Use Each in Clinical Practice

Neuropathy

Shockwave Therapy for Neuropathy

low intensity softwave in use on arm on a table

What Is Li-ESWT & How Does It Work?

Sports medicine practitioners embrace benefits of extracorporeal shock wave therapy

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

Extracorporeal shockwave therapy shows site-specific effects in osteoarthritis of the knee in rats

Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions

Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

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Zimmer enPulsPro Shockwave Machines-

Zimmer enPulsPro Shockwave Machines: Efficacy & Alternatives

Indications for shockwaves in veterinary medicine

Zimmer enPuls Shockwave Systems Compared and Explained for Clinical Practice

Zimmer enPuls Shockwave Machines Compared

Shock waves induce angiogenesis via exosome release

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Prospective randomized trial of accelerated re- epithelization of skin graft donor sites using extracorporeal shock wave therapy

The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

MTS Spark Wave Publications – Science Telegram

Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

Shock waves promote spinal cord repair via TLR32

Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

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Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

Effect of unfocused extracorporeal shock wave therapy on growth factor gene expression in wounds and intact skin of horses. – PubMed – NCBI

Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

​Antibacterial effects of extracorporeal shock waves

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Storz Modulith Shockwave Systems- Mechanisms, Clinical Context, & Alternatives

Storz Modulith Shockwave Machines: Efficacy & Alternatives Explored

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Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

Shock wave therapy enhances neuronal sprouting and improves neuronal survival

7 Red Flags That Signal a Risky Shockwave Device

7 Red Flags That Signal a Risky Shockwave Device

Dr. Lohse Bush, first brain treatments

Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes

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Reduce Inflammation Naturally With Shockwave Therapy

Extracorporeal shock wave treatment of capsular fibrosis after mammary augmentation

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

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Doubts over heart stem-cell therapy

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Analysis of treatment protocols: application of ESWT for wound healing disorders

Motor and Sensory Schwann Cell Phenotype

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ESWT for resident stress fractures in athletes.

Alternatives to Back Surgery Doctors Should Consider

Alternatives to Back Surgery Doctors Should Consider

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Zimmer Shockwave Therapy: Cost, Efficacy, and Alternatives

Shockwave Therapy for Achilles Tendonitis

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softwave device with water water blue background

What are the Side Effects of SoftWave Therapy

​Role of extracorporeal shock wave therapy in management of Peyronie’s disease: A preliminary report

Spark Wave® Therapy Ameliorates Urinary Incontinence

Effects of ESWT on glycosaminoglycan expression during bone healing

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

​Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

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The Assessment of New Bone Formation Induced by Unfocused Extracorporeal Shock Wave Therapy Applied on Pre-Surgical Phase of Distraction Osteogenesis

Piezowave Therapy Efficacy & Alternatives Explained

Piezowave Therapy Efficacy & Alternatives Explained

Effectiveness of extracorporeal shock wave for low back pain (A protocol of systematic review)

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The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

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How Shockwave Therapy Compares to Cortisone Injections

How Shockwave Therapy Compares to Cortisone Injections

Equine extracorporeal shock wave therapy

Effect of shockwave therapy on orthodontic tooth movement

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Best Shockwave Machine for Providers

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Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

The link between shockwaves and innate immunity – the main working mechanism?

Piezowave Shockwave Therapy vs Other Shockwave Devices

Piezowave Shockwave Therapy vs Other Shockwave Devices

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

Storz Duolith Machines- Cost, Efficacy, & Alternatives

Storz Duolith Machines Compared

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

Purple Heart Recipient Uses Innovative Technology to Treat Fellow Veterans

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MTS Spark WavesTM – successfully treating indispositions of the musculoskeletal system

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

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Best Treatment for Tennis Elbow Relief

How Li-ESWT Works for Patients With ED & Other Indications

Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

SoftWave: Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

Using Sound to Battle Opioid Crisis

How Does Shockwave Therapy Work?

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

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Spark Wave® Therapy – a New Method for Peripheral Nerve Regeneration

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Extracorporeal shock wave therapy (ESWT) for the treatment of cellulite e A current metaanalysis​ -(Plastic, Hand and Burn Surgery, University of Schlewig Holstein, Lubeck, Germany​)

Optimization of screw fixation in rat bone with extracorporeal shock waves

ESWT minimizes ischemic tissue necrosis…

ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Plantar Fasciitis Medical Devices That Relieve Pain

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​Update on the efficacy of extracorporeal shockwave treatment for myofascial pain syndrome and fibromyalgia

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LL37 and shock waves

Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice

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Analysis of extracorporeal shock wave therapy for Peyronie’s disease

Treatment of scaphoid waist nonunion

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Comparative SWT Data to Evaluate Competing Technologies in the Treatment of Penile Connective Tissue for Improved Erectile Function

SDSM Spine pain protocol

Storz Masterpuls Machines: Cost, Efficacy, & Alternatives 

Better lithotripsy on the horizon: an interview with James E. Lingeman, MD.

Spark Wave® Therapy Improves Full Thickness Skin Defects

Effective Medical Devices for Temporomandibular Joint Dysfunction

Effective Medical Devices for Temporomandibular Joint Dysfunction

EPAT Shockwave Therapy Efficacy & Alternatives Explained

What Is EPAT Therapy & How Does It Work?

MTS Spark WaveTM Technology and its mechanism of action in wound management

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Best Medical Devices for Treating Tennis & Golfer’s Elbow

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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