PATIENTS    |   BECOME A PROVIDER    |   PROVIDER PORTAL    |   PROVIDER SEARCH    |   REIMBURSEMENT

SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

,

Dr Irwin Goldstein Dinner Presentation – Nashville

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

Extracorporeal shock wave therapy (ESWT) for the treatment of cellulite e A current metaanalysis​ -(Plastic, Hand and Burn Surgery, University of Schlewig Holstein, Lubeck, Germany​)

Top Surgeon: SoftWave ‘a superior way to make tissue want to heal’

SoftWave Therapy for Knees

SoftWave Therapy vs. Stem Wave & Acoustic Wave Devices for Knee Pain

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

LL37 and shock waves

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

, , ,

The Physics of Shock Wave Lithotripsy

The Role of the Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Radical Prostatectomy: A Randomized Clinical Trial

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

Mesenchymal stem cells: Myths and reality

Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

In vitro characterization and simulation of shockwaves by optical phase contrast imaging, computational modeling and acoustic measurement.

Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

,
Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Effective Medical Devices for Treating Tarsal Tunnel Syndrome

Medispec Shockwave Devices- Efficacy & Alternatives

Medispec Shockwave Devices: Efficacy & Alternatives

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin Angiotensin System

Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement—a randomized clinical trial​

Morton's Neuroma

Effective Medical Devices for Treating Morton’s Neuroma

Pickleball Star Riley Newman Speeds Recovery With SoftWave Therapy

Effect of Electrohydraulic Extracorporeal Shockwave Therapy on the Repair of Bone Defects Grafted with Particulate Allografts

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

,
SoftWave on Elbow

Radial Shockwave Therapy Benefits & Alternatives

​Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

Extracorporeal shockwave: mechanisms of action and physiological aspects…

​Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

​Extracorporeal shock wave therapy in periodontics: A new paradigm

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Reduce Inflammation Naturally With Shockwave Therapy

2025 AUA Guidelines on Male Chronic Pelvic Pain: Shockwave Therapy Evidence and Clinical Implications

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Treatment for osteonecrosis of the femoral head

Plantar Fasciitis Medical Devices That Relieve Pain

Plantar Fasciitis Medical Devices That Relieve Pain

Effects of ESWT on glycosaminoglycan expression during bone healing

Treatment of scaphoid waist nonunion

COVID-19 pneumonia: different respiratory treatment for different phenotypes?

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

, ,

Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

opioids united states

FDA Tightens Opioid Warning Labels: Here’s the Non-Invasive Alternative Changing Pain Care

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

Physical Rehabilitation Using Shockwave Therapy

,

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

,

A First Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Extracorporeal Shock Wave Therapy for the Treatment of Peyronie ’s Disease

Case Series of Weekly Low Intensity Shock Wave Therapy for Erectile Dysfunction

Storz Masterpuls Machines: Cost, Efficacy, & Alternatives 

Shockwave Therapy for Achilles Tendonitis

,

Evaluation of a low-intensity shockwave therapy for chronic prostatitis type IIIb/chronic pelvic pain syndrome: a double-blind randomized sham-controlled clinical trial

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

,

Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

Lithotripter outcomes in a community practice setting: Comparison of an electromagnetic and an electrohydraulic lithotripter

Using acoustic therapy to prevent opioid addiction.

Extracorporeal shock waves, a new non-surgical method to treat severe burns

Extracorporeal Shockwave Treatment Impedes Tooth Movement in Rats

,

Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis

Scientific Reports – Gene transfection by shock waves

Cellular signaling pathways modulated by low-intensity extracorporeal shock wave therapy

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Impact of Extracorporeal Shockwave Therapy on Tooth Mobility in Adult Orthodontic Patients: A Randomized Single-Center Placebo-Controlled Clinical Trial

,

Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

Alternatives to Orthopedic Surgery in Outpatient Rehab

Alternatives to Orthopedic Surgery in Outpatient Rehab

Motor and Sensory Schwann Cell Phenotype

, ,

Shockwave Therapy as First-Line Treatment for Peyronie’s Disease: A Prospective Study

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Best Shockwave Machine for Providers

,

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

,

SoftWave vs Shockwave Technology Explained 

,

Effect of Low-energy Extracorporeal Shock Waves on Orthodontic Tooth Movement and Miniscrew Stability

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

Extracorporeal shockwave treatment for chronic diabetic foot ulcers

,

Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

, ,

Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

,

Extracorporeal shockwave therapy (ESWT) ‒ First choice treatment of fracture non-unions

Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Acoustic wave therapy for cellulite, body shaping and fat reduction.

Relief for Back Pain with Innovative Shockwave Therapy

SoftWave ESWT: Redefining Relief for Back Pain with Innovative Shockwave Therapy

,

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

,

​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Erectile Dysfunction before and after results under ultrasound

Macrophage migration induces angiogenesis

Regenerative Treatments for Athletes and Their Role Compared With Surgical Repair

Regenerative Treatments for Athletes Versus Surgical Repair

Zapping chronic tendon pain

The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Non‑surgical Regenerative Treatments Integrating with PT

Non‑surgical Regenerative Treatments Integrating with PT

10 Natural Ways to Find Pain Relief

Extracorporeal shock wave therapy for nonunion of the tibia

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears.

SoftWave’s New Leadership Team Accelerating Commercial Growth and Market Expansion

Cellulite and focused extracorporeal shockwave therapy for non-invasive body contouring: a randomized trial.

Acoustic Field of a Ballistic Shock Wave Therapy Device

Chattanooga Shockwave Devices Compared- What Clinicians Should Evaluate

Chattanooga Shockwave Therapy Devices Compared

Gainswave Machines: Cost, Efficacy, & Alternatives

Gainswave Machines: Cost, Efficacy, & Alternatives

Alternatives to Cortisone Shots for Joint Pain Relief

Alternatives to Cortisone Shots for Joint Pain Relief

Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Three-Time Super Bowl Champion Randy Cross Discovers Pain Relief with SoftWave Therapy

Extracorporeal shock wave therapy: clinical applications and regulation

EPAT Shockwave Therapy Efficacy & Alternatives Explained

What Is EPAT Therapy & How Does It Work?

Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Medical Devices for Treating Carpal Tunnel Syndrome

Angiogenic response upon shock wave treatment of the ischaemic muscle

Stem cells pose risk, offer promise

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

Using Sound to Battle Opioid Crisis

Analysis of treatment protocols: application of ESWT for wound healing disorders

​Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

Renova Shockwave Therapy- What Is It & Does It Work for Patients?

Renova Shockwave Therapy: What Is It & Does It Work for Patients?

Latest Basic Research Abstracts

Purple Heart Recipient Uses Innovative Technology to Treat Fellow Veterans

,

Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptomes in a first-in-man trial

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Effect of penile rehabilitation with low intensity extracorporeal shock wave therapy

Extracorporeal shock wave therapy for the treatment of coccydynia: a series of 23 cases

,

Prospective Randomized Phase II Trial of Accelerated Reepithelialization of Superficial Second-Degree Burn Wounds Using Extracorporeal Shock Wave Therapy

,
Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

EPAT Therapy for Plantar Fasciitis vs Alternatives

Extracorporeal shockwave therapy (ESWT) minimizes ischemic tissue necrosis irrespective of application time and promotes tissue revascularization by stimulating angiogenesis

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

Shock wave therapy alone has no impact on cancer growth

TRT SoftWaves® – a new regenerative therapy for paraplegia

,
Adhesive Capsulitis Management with Advanced Shockwave Therapy

SoftWave: Empowering Adhesive Capsulitis Management with Advanced Shockwave Therapy

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

,

Cellular mechanotransduction: putting all the pieces together again

Best Medical Devices for Treating Patellar Tendinitis

Best Medical Devices for Treating Patellar Tendinitis

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Low–Energy Shockwave Therapy Improves Ischemic Kidney Microcirculation

Extracorporeal shockwave therapy for treatment of keloid scars

Mechano-transduction effect of shock waves

,
How Shockwave Therapy Compares to Cortisone Injections

How Shockwave Therapy Compares to Cortisone Injections

Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial

The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

MTS Science White Paper – Softwave – Pain Therapy

Shockwave Therapy vs Therapeutic Ultrasound- Differences, Benefits, and Outcomes

Shockwave Therapy vs Therapeutic Ultrasound: Differences, Benefits, and Outcomes

Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

SoftWave: Innovating Plantar Fasciitis Relief with Advanced Shockwave Therapy

Best Physical Therapy Devices Clinics Must Have

Best Physical Therapy Devices Clinics Must Have

EPAT Therapy Side Effects & Contraindications

Chattanooga Intelect Shockwave Machine- Evidence, Mechanisms, and Clinical Context

Chattanooga Intelect Shockwave Machine: Efficacy & Alternatives

Shock wave treatment enhances stemness and preserves multipotency

Optimization of screw fixation in rat bone with extracorporeal shock waves

Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

Spark Wave® Therapy Ameliorates Urinary Incontinence

Focal Shockwave Therapy Mechanisms and Efficacy Explained

Focal Shockwave Therapy Mechanisms and Efficacy Explained

Extracorporeal Shock Wave Therapy: Current Evidence

Exploring Regenerative Treatment for Knees After Failed Conservative Care

Regenerative Treatment for Knees That Fail Conservative Care

SoftWave OrthoGold

Best Medical Devices for Treating Wrist Tendonitis 

Shockwave Therapy for Plantar Fasciitis

Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

, , , ,

Biological Principles – Mechanotransduction

Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

,
Pulsewave Therapy- Mechanism of Action and Clinical Indications

Pulsewave Therapy Explained: Mechanism of Action and Clinical Indications

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Effect of shock waves on macrophages

Regenerative Therapies for Hip Pain and Tendinopathy

Regenerative Therapies for Hip Pain and Tendinopathy

The efficacy of ultrasound-guided extracorporeal shockwave therapy in patients with cervical spondylosis and nuchal ligament calcification

,

Spark Wave® Therapy Improves Full Thickness Skin Defects

AUVA letter‒ Successful treatment of delayed and non-union fractures

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

What Is Pneumatic Shockwave Therapy?

What Is Pneumatic Shockwave Therapy?

Extracorporeal shock wave therapy surpresses the early proinflammatory immune response to a severe cutaneous burn injury

Effective Medical Devices for Treating Patellar Tendonitis 

Effective Medical Devices for Treating Patellar Tendonitis 

Alternatives to Surgery

Extracorporeal Shockwave Therapy for Arthritis Treatment

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

Hip Pain Management with Advanced Shockwave Therapy

SoftWave: Revolutionizing Hip Pain Management with Advanced Shockwave Therapy

Effects of Low-Energy Shock Waves on Oral Bacteria

,

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease

Spark Wave® Therapy Improves Cardiac Function

Current concepts of shockwave therapy in stress fractures

Novel Approach to Obtain an Activated Fat Graph

First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Focused vs Radial Shockwave Therapy Machines Explained 

Test43212

Shock wave therapy enhances neuronal sprouting and improves neuronal survival

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

Can You Use a Shockwave Therapy Machine at Home?

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

SoftWave TRT vs Storz Shockwave Machines Compared

Effectiveness of extracorporeal shock wave for low back pain (A protocol of systematic review)

,

Exploring Alternatives to Pain Treatment: Your Path to Natural Relief

Benefits of Spark Wave Therapy in neuronal regeneration

,

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

EPAT Therapy Costs for Patients & Practices

Become a ProviderFind a Provider

Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

Click here to read more.
Read More

LL37 and shock waves

Click here to read more.
Read More

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

Click here to read more.
Read More

Biological Principles – Mechanotransduction

Click here to read more.
Read More

Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
Read More

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Click here to read more.
Read More

IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
Read More

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
Read More

Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
Read More

Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
Read More

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
Read More

Latest Basic Research Abstracts

Click here to read more.
Read More

Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
Read More

Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
Read More

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
Read More

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
Read More

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
Read More

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
Read More

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
Read More
Become a ProviderFind a Provider